What i being tested?
This test detects the presence of herpes simplex virus (HSV) 1 or 2 antibodies of the IgG class, which indicates prior exposure to the virus. It cannot distinguish between the two types of HSV.
Reference Range
The Herpes Simplex Virus 1 and 2 (IgG) test utilizes specific antigens to differentiate between HSV-1 and HSV-2 infections. Results are reported as an index value, and interpretation depends on the value obtained. A value below 0.90 is considered negative, while a value above 1.09 is considered positive. An index value between 0.90 and 1.09 is considered equivocal. However, a positive index result cannot distinguish between recent and past infection. If recent HSV infection is suspected but the results are negative or equivocal, the test should be repeated in 4-6 weeks. It is important to note that the performance characteristics of this test have not been established for pediatric populations, immunocompromised patients, or neonatal screening.
Test Description
What is this test, why should I get it, what happens if I don't get it, what will I find out from this test, and what can I do with this information?
Herpes simplex virus (HSV) is a common viral infection that affects millions of people worldwide. It is a sexually transmitted infection that can cause painful and recurring outbreaks of blisters on the genitals, mouth, or face. HSV is caused by two types of viruses: HSV-1 and HSV-2. HSV-1 is usually responsible for cold sores and fever blisters, while HSV-2 is the primary cause of genital herpes.
The Herpes Simplex Virus 1 and 2 (IgG) blood test, with reflex to HSV-2 inhibition test, is used to detect IgG antibodies specific to HSV types 1 and/or 2 infections. It is used to confirm or rule out possible infection with herpes simplex types 1 and/or 2 virus in prenatal patients in whom HSV-2 infection can cause serious prenatal disease.
Getting this blood test is important for several reasons. First, the test can confirm whether you have been infected with either HSV-1 or HSV-2. Second, the test can determine if you have been exposed to the virus but do not have any symptoms. Third, the test can help guide treatment decisions for those who experience frequent or severe outbreaks.
If you do not get this test, you may not be aware that you have been infected with HSV. Without a diagnosis, you may continue to transmit the virus to others unknowingly, and you may also experience recurrent outbreaks that could have been prevented with appropriate treatment.
The results of this blood test can tell you if you have been infected with HSV-1 or HSV-2, and if so, whether your infection is recent or if you have had it for some time. The test can also tell you if you have been exposed to the virus but do not have any symptoms.
Once you have this information, you can take appropriate steps to manage the infection. If you have recurrent outbreaks, antiviral medications can help reduce their frequency and severity. You can also take steps to reduce the risk of transmitting the virus to others, such as using condoms during sexual activity and avoiding sexual contact during outbreaks.